B7-H7
Broad impact. Precision Therapeutics.

Our Science

NextPoint is launching a new world of precision therapeutics through its leading scientific work on the novel B7-H7/HHLA2 axis. Our team of proven drug developers is advancing a T-cell engager engineered with superior therapeutic index, an antibody-drug-conjugate with our proprietary linker technology, and a multi-functional checkpoint inhibitor.

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 Our innovative approach integrates foundational science with a defined clinical biomarker to identify the right patient population for each B7-H7-directed modality, so that we can deliver first-in-class therapies to a broad range of cancer patients with B7-H7 upregulation including those who do not benefit from currently approved therapies such as PD-1/L1 inhibitors.

Our Pipeline

A unified pipeline to create precision therapeutics that combine direct tumor cell killing and immunomodulation in each single molecule for long-term cancer control, featuring first-in-class assets backed by a strong IP position.

Our Team

World-class Team
We are building a world-class team to help us realize the full potential of our scientific founders’ exciting discoveries and to shape the future of immuno-oncology and tumor-targeting

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Careers

Join us at NextPoint Therapeutics and be part of a team pioneering immuno-oncology advancements
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